Search results for "Factor level"
showing 2 items of 2 documents
Measuring self-esteem in Spanish adolescents: Equivalence across gender and educational levels
2015
Rosenberg's self-esteem scale (RSES) has been applied in many areas of psychology, highlighting the interest in the study of gender differences and educational level. At the same time, there was a methodological debate on its psychometric properties. Evidence points at a scale measuring a single trait confounded by a method factor associated to negatively worded items. The aim of the study is to examine RSES differences due to gender and educational level at the factor level, while controlling for the presence of method effects, in Spanish students. A completely a priori model was separately tested in four subsamples: college men and women, and high school men and women, and an invariance r…
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY
2008
Summary. Background: Combined vitamin K-dependent clotting factor (VKCF) deficiency type 2 (VKCFD2) is a rare bleeding disorder caused by mutated vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) gene. Methods and results: An Italian patient with moderate to severe bleeding tendency was genotyped, and found to be homozygous for the unique VKORC1 mutation (Arg98Trp) so far detected in VKCFD2. The activity levels of VKCFs were differentially reduced, and inversely related to the previously estimated affinity of procoagulant factor propeptides for the γ-carboxylase. The normal (factor IX) or reduced antigen levels (other VKCFs) produced a gradient in specific activities. Vitamin K su…